I have same problem below link.
It is the video about that problem. Please check it and fix please.. I'm very tired cuz that problem.
The Wwise Version is 2021.1.3.7665 and Unreal Version is 4.26.2
I have a curious issue at the moment with Wwise and Unreal Engine 4. When I open my project, then right click on any of my audiokinetic event in my editor, then click "Play Event", it works just fine. But, after that, if I hit Play (to play the game) in the editor, then Stop, and I try to right-click on any of my audiokinetic event and click "Play Event", I won't hear anything anymore, and that issue will stay until I close the engine and reopen the project, which is a really big annoyance.
By doing some tests, it seems that it really is that sequence of events that triggers the issue, because when I open my project and I DON'T try to ''Play Event'' an audiokinetic event, just start playing the game in the editor, then stopping it, and then I try to ''Play Event'', I hear it. And then if I play the game in the editor again, then stop, and try again to ''Play Event'', the issue is there and I won't here it until I restart the engine.